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PRI's Low-Risk Guidelines: 2025 Update

Dec 2025

We receive a lot of questions about our 0-1-2-3 Low-Risk Guidelines for alcohol and drugs, and we know our program instructors do too! Below is a link to recent responses to the most common questions we receive, presented by the PRI Research Team.

Low-Risk Guidelines Info Sheet (Updated 12/30/2025) 

The common questions addressed include:

  • I am seeing increasing amounts of news related to the harms of drinking any amount of alcohol. Why have the Prevention Research Institute (PRI) Low-Risk Guidelines remained the same?
  • What sets PRI’s low-risk guidelines for alcohol apart from those developed by other organizations?
  • Why doesn't PRI lower the low-risk alcohol guidelines for women?
  • Why is zero (0) the only low-risk option for THC?